Polynucleotide Skin Rejuvenation Treatment – Advanced skin quality treatment to support hydration, texture and natural repair.
Polynucleotide skin rejuvenation is a medical cosmetic treatment designed to improve overall skin quality rather than add volume or alter facial expression. It works by supporting the skin’s natural repair processes, helping to improve texture, elasticity and hydration over time.
Our clinic provides polynucleotide skin rejuvenation treatments for patients in Lilydale, the Yarra Valley, and surrounding Melbourne suburbs, following a thorough medical consultation to ensure suitability and realistic outcomes.
This treatment is sometimes referred to as a polynucleotide skin booster and may be known by product names such as Rejuran. In line with Australian regulations, we focus on explaining the treatment and its benefits rather than advertising specific prescription brands.
How does polynucleotide skin rejuvenation work?
Polynucleotide skin rejuvenation is an injectable treatment that targets skin quality at a cellular level. Rather than filling or relaxing muscles, it supports the skin’s own regenerative processes.
Polynucleotides are delivered into the deeper layers of the skin using fine micro-injections. Once delivered, they are believed to:
- Support collagen and elastin production
- Improve skin hydration and elasticity
- Enhance skin texture and tone
- Assist skin recovery and repair
Results develop gradually, making this treatment well suited to patients who prefer subtle, progressive improvement. This is a skin-quality treatment, not a filler and not a wrinkle-relaxing injection.
What areas can be treated?
Polynucleotide skin rejuvenation is commonly used in areas where skin quality has declined, including:
- Face
- Under-eye area
- Neck
- Areas with fine lines or textural change
Suitability is assessed during consultation based on skin condition and treatment goals.
What to expect during treatment
- Consultation and skin assessment
- Topical anaesthetic applied for comfort
- A series of small injections into the treatment area
- Treatment time is usually around 30 minutes
Most patients tolerate the procedure well.
When will I see results?
Results develop gradually as the skin responds over time. Improvements in skin texture, hydration, and overall quality are usually noticed over weeks rather than days.
Multiple sessions (usually 3 ) are recommended for optimal outcomes.
Is this treatment safe?
Polynucleotide skin rejuvenation treatments are regulated in Australia and must be administered by trained health professionals in accordance with guidelines set by the TGA.
As with any injectable procedure, potential risks and side effects will be discussed during consultation.
Disclaimer : The information on this page is general in nature and is not intended as medical advice or as advertising of prescription medicines, medical devices, or therapeutic goods. All consultations and any procedures are provided only after individual clinical assessment by a qualified medical practitioner. Outcomes vary between patients.
Is polynucleotide skin rejuvenation available near Lilydale?
Yes. We provide polynucleotide skin rejuvenation treatments (Also known as polynucleotide skin boosters (e.g. Rejuran) for patients in Lilydale, the Yarra Valley and surrounding Melbourne suburbs following a medical consultation.
Is this treatment suitable for mature skin?
Polynucleotide skin rejuvenation is commonly chosen by patients with early to moderate signs of ageing who wish to improve skin quality, hydration and texture without altering facial structure.
Suitability is assessed individually.
Is this treatment a filler or wrinkle injection?
No. This treatment does not add volume or relax facial muscles. It focuses on improving skin quality by supporting the skin’s natural repair processes.
How many treatments are needed?
3 sessions are recommended for optimal results. Your clinician will recommend a personalised treatment plan during consultation.
Aftercare for Polynucleotide Skin Rejuvenation?
Following treatment, we recommend: Avoid strenuous exercise for 24 hours Avoid excessive heat (saunas, steam rooms) for 24–48 hours Avoid alcohol for 24 hours Avoid rubbing or massaging treated areas unless advised
Mild redness, swelling or small injection marks are common and usually settle within a few days.


